ASBrS 2020: Cosmetic Outcomes With Breast-Conserving Therapy
Posted: Friday, May 29, 2020
Breast-conserving therapy appears to result in good to excellent cosmesis for patients with multiple ipsilateral breast cancer, according to the results of the Alliance Z11102 study. The analysis, which was presented during the 2020 Virtual Scientific Session Official Proceedings of the American Society of Breast Surgeons (ASBrS; Abstract 788207), was conducted by Kari M. Rosenkranz, MD, of Dartmouth Hitchcock Medical Center, Norwich, Vermont, and colleagues.
“We are hopeful [these] new data on cosmesis…will enhance the dialogue regarding best treatments for women with more than one site of disease in a breast and open new options for patients who desire breast preservation,” Dr. Rosenkranz commented in an ASBrS press release. “We believe this could greatly improve patient satisfaction and well-being.”
A total of 216 patients with two or three separate malignant sites within a single breast were enrolled. Each patient underwent a lumpectomy and subsequent radiation therapy. Thirty days after surgery, the patients were assessed for cosmesis by a surgeon. The patients filled out postoperative surveys at eight timepoints from 30 days to 60 months. Cosmesis was assessed on 4-point Likert scale, where 1 indicated excellent and 4 indicated poor cosmetic outcomes. Additionally, patient perception was evaluated on a scale of 1 to 100 using a validated assessment tool known as Breast-Q.
After 30 days, cosmesis was rated as good or excellent by 95.2% of surgeons and 86.8% of patients (P = .001). Approximately 2 years after surgery, the majority of patients (76.6%) reported the cosmetic result was good or excellent. Just 3.7% of patients reported poor cosmesis at this timepoint. Patient-reported cosmetic outcomes did not appear to be impacted by age, number of lesions, incisions, lumpectomies, and size of the largest malignant site. The median Breast-Q satisfaction scores postoperatively and 3 years after surgery were 76.3 and 73.7, respectively.
Disclosure: The study authors reported no conflicts of interest.
2020 Virtual Annual Meeting of the American Society of Breast Surgeons
